Have you been trying to get pregnant for years? Do you feel that your dream of becoming a parent is crushed? If the answer is yes to both the questions, then don’t worry we have got the solution for you. In this era of advancement and technology, you can fulfil your dream of becoming a parent.
IVF or in-vitro fertilization technology is a godsend to humans as it benefits in fighting infertility for couples who have been trying to conceive for years. When you plan to go for IVF treatment, you must know everything about the process involved. It can be intimidating for you so here is what you must know before visiting the doctor.
What is IVF (In Vitro Fertilisation)?
IVF or In-Vitro fertilization also known as assisted reproduction technology (ART) is the process in which your eggs are extracted and a sperm sample is retrieved to initiate the fertilization procedure. The IVF treatment is the finest and reliable solution that can help couples overcome their infertility issues. The technology is identified as the outstanding solution to treat the different infertility problems such as ovulation, blocked Fallopian tubes, and so on. If you have been suffering from any of these issues hampering your parenthood, visiting the best IVF treatment clinic can ensure taking away all your worries.
How Does an IVF Cycle Work?
Before visiting any clinic, it is good to have a slight knowledge of the workings of IVF. Here is the working process of IVF:
- You will be given medications so that your eggs are mature and prepared for fertilisation.
- Your eggs then are taken out to be mixed with sperm in the lab for fertilisation.
- The process starts with the use of a combination of medicines and clinical procedures so that the sperm begins the egg fertilisation.
- Once it is done, the egg is observed in a laboratory to help it turn into a zygote stage, and then it is implanted in the uterus.
- Couples can expect pregnancy if any of the eggs are implanted in the uterine lining.
You must be prepared in advance as there are different steps in IVF and each step requires time and patience.
There is a probability that it may work in the first go, but in most cases, people require more than one round for getting pregnant. The IVF treatment surely enhances pregnancy chances when you and your partner have infertility issues, but there is no assurance that it will work as every individual’s body is different.
How Common is IVF in India?
Well, the infertility rate is increasing rapidly every year. This could be a result of poor lifestyle, food choices, lack of exercise, and increasing pollution. According to the latest data from the United Nations Population Division, the fertility rate in India has been declining consecutively from 1950 to 2023 and is expected to go below. Earlier the fertility rate used to be 5.9 which has narrow down to 2.0 only.
In such cases, IVF treatment helps parents achieve their dream of having a child. According to a report by Ernst & Young, 2.5 million cycles are performed yearly at a global level, out of which India has only 2-2.5 lakh cycles every year.
Who Needs an IVF Treatment?
IVF treatment is mostly for women who are over 40 years old and are trying to get pregnant. But these days, it has become very common because of sedentary lifestyles or genetic issues. So, you must be aware of when to see a doctor. Let’s look at some situations in which IVF is needed:
- Fallopian Tube Damage: If the Fallopian tube is damaged or blocked, egg fertilization becomes difficult. So, in such cases, IVF treatment is the best possible way out.
- Ovulation disorders: These also cause fertilisation problems, so IVF treatment is recommended.
- Endometriosis: This can happen when there is tissue implantation outside of the uterus, impacting other parts’ functioning. This can also lead to shattering your dream of becoming parents, but IVF here again comes to the rescue.
- Age Factor: Women of 30 or 40 years’ age usually these days experience uterine fibroid causing infertility, so IVF is suggested.
- Poor Sperm Morphology: Poor mobility or morphology is another condition that makes it difficult for sperm to fertilise eggs, and IVF treatment remains the only solution to becoming a parent
- Genetic Disorder: The genetic disorder is another condition in which IVF treatment is recommended as there is a high chance of passing on the disorder to the child.
- Health Problems: If a female has cancer and is planning for cancer treatment, then in conditions like this, IVF is the solution for fertility preservation. The eggs are taken out for harvesting and then frozen for further use.
What are the Compulsory Tests Before the IVF Treatment?
IVF doesn’t start when you are undergoing the treatment. It starts way before when you start planning for a child. Here are some compulsory tests before the IVF treatment.
- Ovarian Reserve Testing:
It is a hormone blood test that assists doctors in understanding the number of eggs present in your body. The tests include FSH (follicle-stimulating hormone, Estradiol, and AMH (anti-Mullerian Hormone tests.)
It helps in the evaluation of Fallopian tube patency by inserting the contrast agent.
It is initiated to evaluate the number of sperms available in the male body. Other parameters include motility and shape. It helps the doctor decide whether there is a need for ICSI (Intracytoplasmic Sperm Injection) or not, or if IUI is required.
- A Thyroid Hormonal Test
This is also required to detect the normal body metabolism. If the levels are abnormal, then you’ll be given the medications.
- Infection Screening
Infection screening is to identify different diseases such as Hepatitis C, Hepatitis B, HIV, and Syphilis. These diseases can lead to serious problems, so they need to be detected beforehand.
What are the Steps of the IVF Process?
IVF is done by expert doctors and embryologists in a lab. It basically involves 6 steps from egg stimulation to pregnancy test. Let’s discuss each step in detail for a better understanding:
Step 1: Egg Stimulation
To begin the IVF process, fertility drugs will be given to you, known as stimulation. The drugs will be useful in letting your body know to form more eggs. There will be successful chances of fertilisation if more eggs are produced. Further, you have to undergo transvaginal ultrasounds and some blood tests recommended by the doctor frequently throughout the IVF journey. It will help the doctor to keep a check on the levels of hormones and ovaries.
Step 2: Egg removal
The next process will be egg removal, but before that, you’ll be given a hormone injection to mature the eggs quickly. You have to go through the minor surgery known as the follicular aspiration for egg removal. The doctor will involve the ultrasound wand for guiding a needle through your vagina. There is a device attached to the needle that acts suctioning a single egg at a time.
Well, it might sound painful, right? Sure, it will, but don’t worry. The complete process will be performed with anaesthesia.
Step 3: Sperm Collection from the Partner or Donor
After the eggs are retrieved to continue with the process, your partner’s or donor’s sperm will be collected. High-speed washing is performed to discover the healthiest sperm.
Step 4: Egg Fertilisation
In this IVF process of egg fertilisation, the fertilisation will be encouraged through extracted sperm and eggs. This is called insemination. You may even require ICSI or intracytoplasmic sperm injection to inject the sperm into the embryo directly for fertilisation. Following the process, eggs are preserved cautiously till the time they turn into embryos.
Step 5: Embryo Transfer
After the collection of eggs, you’ll be given another medicine. It is for preparing the uterus lining so that embryos can be received to be inserted back. After the fertilisation is over, i.e. around three to five days, the doctor will insert the embryos into the uterus with a catheter. You should also be aware that there will be the insertion of multiple embryos into the uterus in the belief that there will be implantation of the single embryo itself in the lining.
At times, there is the implantation of more than one embryo in the lining and in such cases, twins or triplets are expected. The IVF process has the tendency to imitate natural reproduction.
Step 6: Pregnancy Test
The last step of the IVF process is the pregnancy test, which will be performed through a blood test after the two weeks of embryo transfer. You’ll also have to undergo the ultrasound test if the tests are positive and in case it’s negative then you need to consult the doctor again. They will recommend other options you can try as IVF treatment.
For more details visit: IVF Process Step by Step
Are There Some Medications Used for IVF Treatment?
Yes, there are some medications used during IVF treatment. While some are injected, absorbed through the skin, or inserted into the vagina, others are taken orally. Your doctor will specify the precise dosage and time depending upon the treatment plan.
Here are some common medications that are suggested:
- Your ovaries are stimulated to generate eggs by the follicle-stimulating hormone (FSH). This is carried out for roughly 14 days.
- Human chorionic gonadotropin (hCG): Usually administered as a last dose to cause your eggs to develop and initiate ovulation.
- Leuprolide acetate is an injection-based gonadotropin-releasing hormone (GnRH) that can be used as a trigger shot or to help regulate the stimulation process.
However, after the embryo transfer, the majority of patients are prescribed estrogen supplements. This hormone helps in thickening their uterine lining. Additionally, progesterone is administered to increase the likelihood that an embryo will implant and develop into a healthy pregnancy. This usually lasts the entire first trimester. These drugs can be administered orally or through injections.
What is the Cost of Undergoing an IVF Cycle?
IVF treatment is not only time-consuming but also expensive. You’ll experience repetitive cycles and countless emotions will come your way both physically and mentally. IVF costs fluctuate because of their cycles. The treatment is expensive as there are medicinal costs, tests and surgery costs. One IVF cycle can cost 1 Lakh to 3.5 lakh. However, this cost can vary based on:
- The IVF centre you choose: Established clinics with higher success rates may charge more.
- Doctor’s fees: Highly experienced specialists might have higher consultation and procedure fees.
- Age and medical history of patient: Age affects the IVF success rate, thereby increasing the cost of IVF for multiple procedures.
- Location of the clinic: The IVF centres in metropolitan cities in India cost more.
- The cost of medicines: Fertility drugs can add to the overall expense.
- No. of IVF cycles: Multiple cycles may be needed, affecting the total cost.
- Cause of infertility: The cost can be affected by the infertility cause (genetic, fallopian tube damage, endometriosis, etc)
- Additional procedures involved: Techniques like Intracytoplasmic Sperm Injection (ICSI) or Preimplantation Genetic Testing (PGT) can increase costs.
So, if IVF is the only solution for you to experience parenthood, you must first pay a visit to the IVF infertility clinic and talk to your doctor. They can guide you better with every penny you’ll be spending on the treatment. At Crysta IVF, to make the treatment more affordable, we offer a no-cost EMI option to fulfil your dream of parenthood.
Also Read: Facts You Didn’t Know About Cost Of IVF Treatment In India
Cost of IVF in India Based on Different Cities
The cost of IVF can vary based on the city where you are undergoing the treatment. Here is the average cost of IVF in different cities in India:
| City of IVF Treatment | Approximate Cost Range (INR) |
|---|---|
| IVF cost in Delhi | ₹1,00,000 – ₹2,50,000 |
| IVF cost in Mumbai | ₹1,50,000 – ₹3,00,000 |
| IVF cost in Chennai | ₹1,00,000 – ₹2,50,000 |
| IVF cost in Bangalore | ₹1,40,000 – ₹2,75,000 |
| IVF cost in Kolkata | ₹1,00,000 – ₹2,50,000 |
| IVF cost in Hyderabad | ₹1,00,000 – ₹2,50,000 |
| IVF cost in Pune | ₹1,50,000 – ₹2,75,000 |
| IVF cost in Ahmedabad | ₹1,00,000 – ₹2,50,000 |
Note: Please note that these figures are approximate and can vary based on individual clinics and specific treatment requirements.
How Can You Save Costs During IVF Treatment?
There are certain ways by which you can save the cost of IVF treatment. It includes:
- Research and compare IVF centers for affordable yet reputable options.
- Look for clinics offering package deals that include medications, consultations, and procedures.
- IVF costs vary across cities; hence, choose a city with lower cost.
- Some clinics offer low-cost IVF cycles with fewer medications, reducing overall expenses.
- Look for EMI options, discounts, or government schemes that support IVF treatment.
- Frozen embryo transfer (FET) is often cheaper than a fresh IVF cycle.
- Compare prices at different pharmacies and ask your doctor for cheaper alternatives if possible.
- Maintaining a healthy lifestyle can improve IVF success in fewer cycles, saving additional costs.
What is the Success Rate of IVF Cycle?
The success rate of IVF depends on several factors, including a man’s & woman’s age, overall health, the quality of eggs and sperm, and the doctor’s expertise. On average, the success rate of IVF ranges from 30% to 50% per cycle, with younger women having a higher chance of success.
Factors like embryo quality, lifestyle habits, and the use of advanced techniques such as ICSI (Intracytoplasmic Sperm Injection) or PGT (Preimplantation Genetic Testing) can also influence success rates. Multiple cycles may be needed for a successful pregnancy, so consulting with a fertility expert for personalised advice is essential.
IVF Success Rate by Age
The success rate of any IVF depends highly upon the age of the female. However, it is also dependent on other factors such as the quality of eggs & sperm, the doctor’s expertise, the cause of the problem, etc. According to the latest data of the IVF care centre, here is the IVF Success rate by age:
| Age of the Patient | IVF Success Rate per Embryo Transfer |
| Women under 35 | ~ 32% |
| Ages 35 to 39 | 25% to 19% |
| Ages 40 to 44 | 11% to 5% |
| Ages over 44 | ~ 4% |
Source: nhs.uk
These figures highlight the decline in fertility as women age, emphasizing the importance of considering age when evaluating IVF treatment options. It’s essential to consult with a fertility specialist to understand individual success probabilities and tailor treatment plans accordingly.
For more details read: Age limit for IVF Treatment
What to Expect After Undergoing IVF Treatment?
After undergoing an IVF treatment, you might experience some mild symptoms in your body, but not all women experience them. Here are some symptoms:
- Mild cramps
- Breast tenderness
- Spotting
- Constipation
- Dizziness
These symptoms might disappear after a week or so, but if the symptoms persist for even a longer time, you must immediately connect with a fertility expert.
What are the Side Effects of the IVF Process?
The IVF process also has risks and probable side effects that you usually experience with any medicine or medical process. These side effects may include infection, bleeding, headaches, mood swings, bloating, cramping and allergic reactions. You can always get in touch with your doctors if you have any doubts or apprehensions.
Some common risks of IVF include:
- Ectopic Pregnancy
- Complications during egg retrieval
- Abdominal pain and nausea
- Miscarriage
- Twins Birth
IVF treatment can be very traumatic for anyone (partner and family). There are even people who have to experience depression and stress during the process. So, it is always better to talk with people who have experienced infertility issues or have undergone the IVF process. It will help you overcome all your fears. You can also consider reaching therapists and counsellors, as they are the best sources when you are experiencing discomfort.
Important Factors to Consider Before Choosing the Best IVF Centre
One of the most important decisions before starting your IVF journey is choosing the best IVF centre. Remember, a bad decision can make the whole IVF process more problematic, hence, it is important to choose the right IVF centre before proceeding.
- Doctor’s Speciality
It can be difficult to find a fertility specialist who meets your needs. Trust and the doctor-patient relationship are critical to any treatment. Make sure the fertility doctor you choose is highly qualified, knowledgeable and someone you feel at ease with.
- The Centres Quality for IVF
When it comes to IVF treatment, quality is crucial. Locating an IVF facility with a strong commitment to quality is crucial. The following are the essential certifications, standards, and quality compliances:
- The Indian Council of Medical Research (ICMR) should certify it.
- The ART law’s criteria, guidelines, and restrictions should be adhered to by the fertility clinic.
- Personalised Care and Treatment
A fertility therapy can be a very emotional experience. Choosing an IVF facility that provides individualised, compassionate care throughout the IVF process, as well as mental health assistance, is crucial. Seek out a facility with personnel who can address your issues and needs.
- Facilities Offered
Make the decision to visit a clinic that has the newest, most advanced equipment and technology. In vitro maturation (IVM), assisted hatching, intrauterine insemination (IUI), and other fertility treatments should be performed in specialised facilities that are maintained in accordance with standards and norms at an IVF clinic.
- Freezing or Preserving Embryos
For couples who are unable to prepare for conception right away, embryo freezing is a necessary facility and cutting-edge technology. During an IVF procedure, not every embryo created is used for implantation. Liquid nitrogen is utilised to freeze the extra embryos for later use. Therefore, it’s critical to find out if the IVF facility offers embryo freezing.
- Success Rates for IVF
Progress in reproductive medicine is always being made to improve success rates. Since then, IVF technology has helped millions of parents welcome their biological children. The couple should know the success rates before committing to an IVF facility so they may make an informed decision and have reasonable expectations.
- Cost of an IVF Package
The cost of fertility treatments is high. It is crucial to understand the cost of the IVF package before beginning any reproductive treatment. You can plan everything financially in advance by knowing the cost of the IVF package. Select an IVF facility with no hidden fees and a clear pricing structure.
- The Clinic’s Location
Although it might not seem significant, the location of the IVF clinic should be taken into account. Because of the frequent visits, choosing a centre that is conveniently placed not only saves time but also lessens the stress of travelling.
What Questions Should I Ask with My Fertility Provider?
Deciding to undergo IVF and choosing a fertility clinic is crucial. Once you are done researching the clinic, you must be prepared to shortlist some questions to ask your doctors. Here are some questions you must definitely ask your doctors:
- What is the success rate of IVF?
- Is IVF the only option for infertility?
- What are the chances of multiple births?
- What is the cost of the IVF procedure?
- Is it possible to keep and freeze embryos?
- Is sex selection permitted?
The very first thing you need to do to deal with the infertility issue is to speak with a doctor. Once you are confident enough to discuss your problem and feel comfortable with your doctor, the IVF procedure will become simpler for you.
What are the Do’s and Don’ts of IVF Treatment?
While undergoing IVF treatment, there are a few things you must take care of. Here are a few things you must take care of before undergoing IVF treatment:
| Dos of IVF Treatment | Don’ts of IVF Treatment |
| Follow your doctor’s instructions. | Don’t skip your medication. |
| Maintain a balanced, healthy diet rich in nutrients. | Avoid processed foods, alcohol, and caffeine. |
| Get adequate rest and manage stress through meditation. | Don’t overexert yourself with strenuous physical activities. |
| Stay hydrated by drinking plenty of water. | Don’t consume sugary drinks or excessive caffeine. |
| Take prescribed prenatal vitamins, especially folic acid. | Don’t self-medicate or take unapproved supplements. |
| Maintain a positive attitude and emotional well-being. | Don’t stress too much or dwell on negative outcomes. |
| Inform your doctor about any side effects immediately. | Don’t ignore symptoms like severe cramping or bleeding. |
| Attend all follow-up appointments regularly. | Don’t miss any scheduled visits or monitoring sessions. |
| Keep your partner involved and maintain good communication. | Don’t isolate yourself or neglect your mental health. |
| Stay updated on your treatment plan and progress. | Don’t rely on unverified information or myths. |
Frequently Asked Questions Related to IVF Treatment
Ques: Who is IVF recommended for?
Ans: IVF is recommended for couples with infertility issues like blocked fallopian tubes, male infertility, unexplained infertility, or age-related fertility decline.
Ques: How long does the IVF process take?
Ans: The IVF process typically takes around 4-6 weeks, from ovarian stimulation to embryo transfer.
Ques: What is the success rate of IVF?
Ans: The success rate of IVF varies by age, ranging from 40% for women under 35 to around 5% for women over 42.
Ques: Are there any side effects of IVF?
Ans: Generally, there are no side effects of IVF, but some women might feel some symptoms, which include bloating, cramping, mood swings, and in rare cases, ovarian hyperstimulation syndrome (OHSS).
Ques: Is IVF painful?
Ans: The process of IVF may involve mild discomfort, especially during egg retrieval and hormone injections, but pain management options are available. However, not everyone might feel the symptoms.
Ques: How many IVF cycles are usually needed?
Ans: On average, couples may need 2-3 IVF cycles for a successful pregnancy, though it varies based on individual health factors.
Ques: Is IVF safe for both the mother and baby?
ANs: Yes, IVF is generally safe. However, there is a slightly higher risk of multiple pregnancies and low birth weight.
Ques: Can IVF guarantee a pregnancy?
ANs: No, IVF does not guarantee pregnancy, but it significantly increases the chances for many couples facing infertility.
Ques: Can IVF be done with donor eggs or sperm?
Ans: Yes, IVF can be performed using donor eggs, sperm, or embryos if needed.
Ques: How many embryos are usually transferred during IVF?
Ans: Typically, one or two embryos are transferred to reduce the risk of multiple pregnancies.
Ques: What is embryo freezing, and why is it done?
Ans: Embryo freezing preserves unused embryos for future use. It’s done to increase the chances of future pregnancies without repeating the entire IVF cycle.
Ques: Is bed rest required after embryo transfer?
Ans: Complete bed rest is not necessary. Light activities are usually recommended, but strenuous activities should be avoided after embryo transfer.
Ques: How soon can a pregnancy test be taken after IVF?
ANs: A blood test for pregnancy (beta-hCG) is typically done 10-14 days after the embryo transfer during an IVF cycle.
Ques: Can stress affect IVF outcomes?
Ans: Yes, excessive stress may impact hormonal balance, but moderate stress is generally recommended to the patients.
Ques: How much does IVF cost?
Ans: An IVF cycle can cost between ₹1.5 to ₹2.5 lakhs per cycle in India, depending on the clinic and additional procedures.
Ques: Can IVF be repeated if it fails?
Ans: Yes, IVF can be repeated if it fails for the first time. Your doctor may recommend adjustments in the protocol to increase the chances of success.
guide you better with every penny you’ll be spending on the treatment. So, before making the decision on IVF treatment, you need to ensure its affordability.
